Artemisa is the capital of Artemisa province in Western Cuba. Before 2011 it was a part of Havana province.
There are two trains per day from Havana, but knowing the unreliability of Cuba's train system, don't count on it. Hiring a car is your best option. There are also collective taxis along the carretera central.
There is no public transport.
Options are very limited. There is one hotel. Ask locally about a casa particular.