Holdrege is in South Central Nebraska. Understand Get in By car US Highways 6, 34, and 183. By train Amtrak, 100 West Ave. Holdrege is served once daily in each direction by the California Zephyr. Get around See Nebraska Prairie Museum, 2701 Burlington St. Apr 1-Oct 31: M-F 9AM-5PM, Sa-Su 1PM-5PM; Nov 1-Mar 31: M-F 9AM-4PM, Sa-Su 1PM-4PM. Recommended donation $5 adults, $2 children Do Buy Eat Drink Sleep Connect Go next