San Diego is a small town on the South Texas Plains. Understand Get in TX-44 connects from Alice and Corpus Christi to the east TX-359 connects the city with Laredo on the Mexican border, and with Alice, about 8 miles to the east. Get around See Do Buy Eat Taqueria El Jalisiense, 501 E Gravis Ave, +1 361 279-8998. Tex-Mex, 210 N Benavides St, +1 361 279-7224. Drink Sleep Connect Go next